The Blog.

Notes from the protocol — what we've learned, what the literature actually says, and what we're testing next.
Protocols

Retatrutide vs Tirzepatide: a practical comparison

Two GLP-1s, two pharmacokinetic profiles, two very different titration curves. Here's how we'd decide between them, based on what the trials actually show.

May 18, 20268 min read
Biomarkers

How to read a free testosterone trend line

Total T tells you almost nothing. Free T tells you most of the story. This is how to read the shape, not just the number.

May 12, 20266 min read
Protocols

Reconstitution math, without the anxiety

Most reconstitution errors are not math errors — they're attention errors. A two-step process that removes every chance for either.

May 4, 20265 min read
Nutrition

GLP-1 plateau? Read your macros first

Nine times out of ten, a stalled GLP-1 protocol isn't a dose problem — it's a protein problem. Here's how to tell the difference.

April 27, 20267 min read
Science

BPC-157: what the literature actually says

Strip out the forum noise and you're left with a small, surprisingly consistent body of work. Here's our annotated summary.

April 21, 20269 min read
Recovery

Sleep, HRV, and why your stack stalls

The fastest way to predict whether your next titration will work isn't a biomarker — it's last week's HRV trend.

April 14, 20266 min read
Biomarkers

The case for monthly bloodwork

Quarterly was a print-era number. If you're titrating, monthly is the floor — and here's how to pay for it without going broke.

April 6, 20265 min read
Protocols

Cycling off: a quiet, underrated skill

Knowing how to stop a peptide cleanly is half the protocol. We rarely talk about it. We should.

March 30, 20267 min read
Recovery

Photo logging: why three angles beat the scale

The scale lags by 2–3 weeks. Photos don't. A short note on how we use them and what to discard.

March 24, 20264 min read
Nutrition

Glucose awareness without a CGM

Not everyone wants a sensor stuck to their arm. Here's the next-best practice, with cited reference ranges.

March 18, 20266 min read