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The Independent
Peptide Encyclopedia.

An evidence-graded peptide reference. Every compound carries a research grade, dosing drawn from published protocols, and links to the primary literature.

54 compounds · 324 reference sections · graded, not ranked

Notable Peptides

All 54 compounds

hCG (Human Chorionic Gonadotropin)

growth & hormonesSgrade

An FDA-approved hormone that mimics LH, restoring the body's own testosterone and sperm production — the label dates to 1962.

Retatrutide

fat loss & metabolismAgrade

An investigational triple GIP/GLP-1/glucagon receptor agonist producing some of the largest average weight reductions reported for a single agent.

BPC-157 + TB-500 Blend

recovery & healingBgrade

A single-vial blend of BPC-157 and TB-500 — local plus systemic tissue repair in one convenient injection.

GLOW Blend

skin & aestheticsBgrade

A copper-peptide-forward single-vial blend pairing GHK-Cu's skin remodeling with BPC-157 and TB-500's tissue-repair support.

Tesamorelin + Ipamorelin Blend

growth & GHBgrade

A single-vial blend pairing FDA-approved GHRH analog Tesamorelin with the selective ghrelin-agonist Ipamorelin for a combined GH pulse in one injection.

BPC-157

recovery & healingCgrade

A synthetic peptide derived from a gastric protein, used for soft-tissue healing, gut repair, and reducing inflammation.

CJC-1295 (no-DAC) + Ipamorelin Blend

growth & GHCgrade

A single-vial blend pairing short-acting CJC-1295 (no-DAC) with Ipamorelin for a clean, physiological GH pulse in one shot.

Ipamorelin

growth & GHCgrade

A selective GH secretagogue (ghrelin mimetic) that raises growth hormone with minimal effect on cortisol or appetite.

KLOW Blend

recovery & healingCgrade

A single-vial 4-peptide blend combining GHK-Cu, KPV, BPC-157, and TB-500 — the most comprehensive of the popular research recovery blends.

CJC-1295 (DAC)

growth & GHDgrade

The long-acting form of CJC-1295: a DAC tag extends its half-life to days for a sustained growth hormone bleed.

TB-500

recovery & healingDgrade

A synthetic fragment of Thymosin Beta-4 used for systemic recovery, muscle repair, and improved flexibility.

Exenatide

fat loss & metabolismSgrade

The first-in-class GLP-1 receptor agonist, derived from a peptide found in Gila monster saliva — sold as Byetta and Bydureon.

Liraglutide

fat loss & metabolismSgrade

A once-daily GLP-1 receptor agonist — the class predecessor to semaglutide and tirzepatide, still widely prescribed under Victoza and Saxenda.

Orforglipron

fat loss & metabolismSgrade

The first oral, non-peptide GLP-1 receptor agonist pill with no food or water restrictions — FDA-approved in 2026 as Foundayo.

PT-141

sexual healthSgrade

A melanocortin agonist used to enhance sexual desire and arousal in both men and women, acting on the brain rather than vasculature.

Semaglutide

fat loss & metabolismSgrade

A GLP-1 receptor agonist that reduces appetite and improves glucose control, widely used for weight loss.

Somatropin (HGH)

growth & hormonesSgrade

Recombinant human growth hormone — a 191-amino-acid polypeptide identical to the body's own pituitary GH, sold under brands including Humatrope and Genotropin.

Tesamorelin

fat loss & metabolismSgrade

An FDA-approved GHRH analog known for reducing stubborn visceral fat and raising IGF-1 levels.

Tirzepatide

fat loss & metabolismSgrade

A dual GIP/GLP-1 receptor agonist offering strong appetite suppression and glucose control, often more potent than semaglutide.

MK-677

growth & GHAgrade

An oral ghrelin-receptor agonist that raises growth hormone and IGF-1 around the clock without injections.

Thymosin Alpha-1

longevity & healthspanAgrade

A 28-amino-acid thymic peptide approved in 35+ countries as Zadaxin for immune support — but never FDA-approved in the United States.

Kisspeptin-10

sexual healthBgrade

A decapeptide fragment of human kisspeptin, sitting upstream of the entire reproductive hormone axis by triggering GnRH release.

Melanotan I (Afamelanotide)

skin & aestheticsBgrade

The only melanotan with FDA approval — cleared as Scenesse in 2019 for a rare disorder where sunlight causes severe skin pain, not for general tanning.

Melanotan II

skin & aestheticsBgrade

A synthetic melanocortin agonist used to darken skin (tanning), with libido effects and notable safety cautions.

Best Peptides For...

All guides

Weight Loss

6 Min ReadPopular

Compare the most effective peptides for weight loss and fat loss. Evidence-based rankings of semaglutide, tirzepatide, retatrutide, and more.

Recovery

5 Min ReadPopular

Compare the best peptides for injury recovery, tissue repair, and healing. Evidence-based rankings of BPC-157, TB-500, and more.

Muscle Growth

6 Min ReadPopular

Compare the best peptides for muscle growth, recovery, and body composition. Evidence-based rankings of CJC-1295, ipamorelin, and more.

Anti-Aging

6 Min ReadPopular

Compare the best anti-aging peptides for longevity, skin health, cognitive function, and cellular repair. Evidence-based rankings.

Skin Health

5 Min ReadPopular

Compare the best peptides for skin health, anti-aging, collagen production, and wound healing. Evidence-based rankings.

Sleep

4 Min Read

Compare the best peptides for sleep quality: DSIP, ipamorelin, CJC-1295, Selank, epithalon. Evidence-based rankings with dosing.

Gut Health

4 Min Read

Compare the best peptides for gut health, intestinal permeability, and inflammatory bowel conditions. Evidence-based rankings.

Joint Health

4 Min Read

Compare the best peptides for joint health, tendon repair, and connective tissue recovery. Evidence-based rankings.

Cognitive Enhancement

5 Min Read

Compare the best nootropic peptides for focus, memory, and neuroprotection. Evidence-based rankings of Semax, Selank, and more.

Hair Growth

3 Min Read

Compare the best peptides for hair growth and follicle health. Evidence-based rankings of GHK-Cu, AHK-Cu, and more.

Beginners

6 Min Read

The peptides most often started first, ranked by evidence quality and safety profile rather than popularity.

Sexual Health

4 Min Read

Compare peptides for libido, arousal, and hormonal support. Evidence-based rankings of PT-141, kisspeptin-10, and more.

Immune Support

4 Min Read

Compare peptides for immune modulation and antimicrobial defence. Evidence-based rankings of thymosin alpha-1, LL-37, and more.

Peptide Comparisons

Semaglutide vs Tirzepatide

3 Min ReadPopular

Semaglutide vs Tirzepatide: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

BPC-157 vs TB-500

3 Min ReadPopular

BPC-157 vs TB-500: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

CJC-1295 (DAC) vs Ipamorelin

3 Min ReadPopular

CJC-1295 (DAC) vs Ipamorelin: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

Liraglutide vs Semaglutide

3 Min Read

Liraglutide vs Semaglutide: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

Semaglutide vs Retatrutide

3 Min ReadPopular

Semaglutide vs Retatrutide: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

Sermorelin vs CJC-1295 (DAC)

3 Min Read

Sermorelin vs CJC-1295 (DAC): mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

Ipamorelin vs GHRP-6

3 Min Read

Ipamorelin vs GHRP-6: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

Selank vs Semax

3 Min ReadPopular

Selank vs Semax: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

GHK-Cu vs BPC-157

3 Min Read

GHK-Cu vs BPC-157: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

BPC-157 vs KPV

3 Min Read

BPC-157 vs KPV: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

PT-141 vs Melanotan II

3 Min ReadPopular

PT-141 vs Melanotan II: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

Tirzepatide vs Retatrutide

3 Min ReadPopular

Tirzepatide vs Retatrutide: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

GHRP-2 vs GHRP-6

3 Min Read

GHRP-2 vs GHRP-6: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

Epithalon vs SS-31 (Elamipretide)

3 Min Read

Epithalon vs SS-31 (Elamipretide): mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

Tesamorelin vs Ipamorelin

3 Min Read

Tesamorelin vs Ipamorelin: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

Thymosin Alpha-1 vs TB-500

3 Min Read

Thymosin Alpha-1 vs TB-500: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

Semaglutide vs Orforglipron

3 Min Read

Semaglutide vs Orforglipron: mechanism, dosing, evidence grade, and side effects compared side by side, with citations.

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