Longevity Peptides
Healthspan, mitochondrial, and immune compounds, separated by whether the data is human or rodent.
Thymosin Alpha-1
A 28-amino-acid thymic peptide approved in 35+ countries as Zadaxin for immune support — but never FDA-approved in the United States.
Oxytocin
A naturally occurring nonapeptide — FDA-approved as Pitocin for labor, and separately studied off-label (intranasal) for social bonding and stress research.
SS-31 (Elamipretide)
A mitochondria-targeting tetrapeptide, FDA-approved in September 2025 for Barth syndrome — a real approval in one narrow rare disease, not a general muscle or longevity drug.
Humanin
A mitochondrial-derived peptide discovered protecting neurons from Alzheimer's-linked toxicity — cell and rodent data only, no human trial exists.
MOTS-c
A mitochondrial-derived peptide that supports metabolic flexibility, insulin sensitivity, and exercise capacity.
VIP (Vasoactive Intestinal Peptide)
A 28-amino-acid neuropeptide with broad vasodilator, anti-inflammatory, and immunomodulatory effects, cleared from plasma within about a minute.
Epithalon
A synthetic tetrapeptide analog of a natural pineal gland peptide, studied for telomerase activation and circadian regulation.
SLU-PP-332
A pan-ERR agonist nicknamed the 'exercise pill' — reduced fat mass and raised fatty-acid oxidation in obese mice, with zero human trials as of 2026.
SLU-PP-915
The first orally-active pan-ERR agonist — raised exercise capacity in mice even when dosed orally, where its predecessor SLU-PP-332 needed injection.
Adamax
A synthetic nonapeptide analog of Semax with N-terminal acetylation and adamantyl C-terminal modification, studied for enhanced BDNF signaling and blood-brain barrier penetration.
Pinealon
A Khavinson-group tripeptide bioregulator, studied preclinically for neuroprotective and cognitive-aging effects.