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Performance

Performance Peptides

Growth hormone secretagogues, GHRH analogs, and hormonal compounds, with the IGF-1 data behind them.

S 3A 1B 2C 6D 2F 2What the grades mean

Performance compounds mostly work upstream: rather than supplying growth hormone, they push the pituitary to release its own. GHRH analogs (sermorelin, tesamorelin, CJC-1295) and ghrelin mimetics (ipamorelin, MK-677) raise IGF-1, and IGF-1 is the biomarker nearly every study in this category reports. A handful hold real approvals, tesamorelin for visceral fat and somatropin for deficiency; most do not. Read the grade beside each name before the claim.

hCG (Human Chorionic Gonadotropin)

S-grade

An FDA-approved hormone that mimics LH, restoring the body's own testosterone and sperm production, the label dates to 1962.

TRT AncillaryFDA-approved

Tesamorelin + Ipamorelin Blend

B-grade

A single-vial blend pairing FDA-approved GHRH analog Tesamorelin with the selective ghrelin-agonist Ipamorelin for a combined GH pulse in one injection.

GH ReleaseRecovery

CJC-1295 (no-DAC) + Ipamorelin Blend

C-grade

A single-vial blend pairing short-acting CJC-1295 (no-DAC) with Ipamorelin for a clean, physiological GH pulse in one shot.

GH ReleaseRecovery

Ipamorelin

C-grade

A selective GH secretagogue (ghrelin mimetic) that raises growth hormone with minimal effect on cortisol or appetite.

GH SupportLean Growth

CJC-1295 (DAC)

D-grade

The long-acting form of CJC-1295: a DAC tag extends its half-life to days for a sustained growth hormone bleed.

GH SupportRecovery

PT-141

S-grade

A melanocortin agonist used to enhance sexual desire and arousal in both men and women, acting on the brain rather than vasculature.

LibidoFDA-approved

Somatropin (HGH)

S-grade

Recombinant human growth hormone, a 191-amino-acid polypeptide identical to the body's own pituitary GH, sold under brands including Humatrope and Genotropin.

Growth HormoneFDA-approved

MK-677

A-grade

An oral ghrelin-receptor agonist that raises growth hormone and IGF-1 around the clock without injections.

GH SupportLean Growth

Kisspeptin-10

B-grade

A decapeptide fragment of human kisspeptin, sitting upstream of the entire reproductive hormone axis by triggering GnRH release.

Reproductive HormonesLibido

CJC-1295 (no-DAC)

C-grade

The short-acting form of CJC-1295 (Mod GRF 1-29): a sharp, pulsatile GH release that closely mimics natural rhythm.

GH PulseLean Growth

GHRP-2

C-grade

A potent growth hormone releasing peptide (ghrelin mimetic) that triggers a strong GH pulse, often stacked with a GHRH.

GH ReleaseMuscle Growth

Gonadorelin

C-grade

A synthetic copy of GnRH, the body's own upstream trigger for testosterone, used by TRT clinics to keep the testes active during therapy.

TRT AncillaryFDA-approved

Sermorelin

C-grade

A classic 29-amino-acid GHRH fragment, historically FDA-approved as Geref, clears fast, keeping GH release in its natural pulsatile rhythm.

GH ReleaseSleep

GHRP-6

D-grade

An early growth hormone releasing peptide known for a strong GH pulse and pronounced appetite stimulation.

GH ReleaseAppetite

Follistatin-344

F-grade

A myostatin-blocking peptide with real biology behind it, but the injectable product sold to researchers has essentially no human evidence of its own.

Myostatin InhibitionMuscle Growth

IGF-1 LR3

F-grade

A long-acting analog of insulin-like growth factor 1 that drives muscle growth and recovery, with a strong effect on blood sugar.

Muscle GrowthRecovery

Guides in this category

Performance peptide questions

How many performance peptides are there?

This library covers 16 performance compounds, each graded from S (regulatory approval) to F (no usable evidence).

Which performance peptide has the strongest evidence?

hCG (Human Chorionic Gonadotropin) carries the highest research grade in this category at S. An FDA-approved hormone that mimics LH, restoring the body's own testosterone and sperm production, the label dates to 1962.

What does the research grade mean?

The grade describes how well a compound has been measured in humans, not how well it works. S means regulatory approval; D means animal data only. Popularity and anecdote do not affect it.

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