Exenatide Dosage and Protocols
Exenatide dosage protocols reported in published research, plus reconstitution and storage.
Two Formulations
Byetta is dosed at 5mcg subcutaneously twice daily, within 60 minutes before the two largest meals of the day, increasing to 10mcg BID after one month if tolerated. Bydureon (extended-release microspheres) is dosed at a fixed 2mg once weekly, any time of day, without regard to meals — the two formulations are not interchangeable on a mcg-for-mcg basis.
Reported protocol doses
Standard dose5–10 mcg BID · 2mg weekly (XR)
Frequencysee formulation
Routessubcutaneous
Doses shown are those reported in published research, not a recommendation.