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5-Amino-1MQ Side Effects and Safety

Reported 5-Amino-1MQ side effects, contraindications, and safety signals.

RE
Compiled from published research · Last updated 2026-08-18T00:00:00.000Z

No Human Safety Data

Because no human trial has been published, there is no characterized human side-effect profile for 5-Amino-1MQ. Active malignancy is treated as a precautionary contraindication given NNMT's broader role in cellular methylation metabolism, which has documented links to some cancer biology in unrelated research contexts.

Contraindications

  • pregnancy
  • active malignancy

References

  1. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice · Neelakantan H, et al. · 2018
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