Sermorelin Pharmacokinetics
Sermorelin half-life, absorption, routes of administration, and clearance.
Very Short Half-Life
Sermorelin's half-life of roughly 10-20 minutes is what produces its brief, physiological-style GH pulse rather than sustained receptor stimulation — the same short-acting design philosophy behind CJC-1295 (no-DAC).
Physicochemical and PK profile
- Sequence
- GHRH(1-29) — 29-amino-acid fragment of native growth hormone-releasing hormone
- Half-Life
- ~10-20 minutes
- Storage
- Store the lyophilized vial refrigerated (2-8°C) or at -20°C, away from light. Once reconstituted, keep refrigerated at 2-8°C and use promptly.
References
- Khorram GHRH(1-29) body composition study · Khorram O, et al. · 1997