hCG (Human Chorionic Gonadotropin) Research Evidence

hCG's FDA approval for hypogonadotropic hypogonadism and fertility use dates back to 1962, one of the oldest, most established hormone therapies in this catalog. In a 2019 study (Madhusoodanan et al., n=20) of men taking hCG as monotherapy, testosterone rose approximately 50%, with roughly half reporting symptom improvement, low libido and erectile dysfunction were each the presenting complaint in 45% of participants.

hCG is prescription-only and FDA-approved, with an exceptionally long track record. It should be obtained through a licensed prescriber and pharmacy. Note: the popular 'hCG diet' (very-low-calorie dieting combined with hCG for weight loss) is not part of hCG's approved label or supported by its evidence base, the FDA has specifically warned against marketing hCG for weight loss.