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Gonadorelin Side Effects and Safety

Reported Gonadorelin side effects, contraindications, and safety signals.

RE
Compiled from published research · Last updated 2026-07-24T00:00:00.000Z

Generally Mild

Reported effects are generally mild — injection-site irritation and occasional headache. Because it stimulates the same axis as exogenous hormone therapy, hormone-sensitive cancers are treated as a contraindication.

Contraindications

  • pregnancy
  • hormone-sensitive cancers
  • known hypersensitivity

References

  1. Induction of testicular growth and spermatogenesis by pulsatile, intravenous administration of gonadotrophin-releasing hormone · Delemarre-van de Waal HA · 1993
All Gonadorelin sections

hCG (Human Chorionic Gonadotropin)

growth & hormonesSgrade

An FDA-approved hormone that mimics LH, restoring the body's own testosterone and sperm production — the label dates to 1962.

Tesamorelin + Ipamorelin Blend

growth & GHBgrade

A single-vial blend pairing FDA-approved GHRH analog Tesamorelin with the selective ghrelin-agonist Ipamorelin for a combined GH pulse in one injection.

CJC-1295 (no-DAC) + Ipamorelin Blend

growth & GHCgrade

A single-vial blend pairing short-acting CJC-1295 (no-DAC) with Ipamorelin for a clean, physiological GH pulse in one shot.

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