Gonadorelin Pharmacokinetics
Gonadorelin half-life, absorption, routes of administration, and clearance.
Very Short Half-Life
Gonadorelin has a plasma half-life of roughly 10-40 minutes, consistent with native GnRH's naturally pulsatile secretion pattern, this short half-life is why it's dosed frequently rather than weekly, unlike longer-acting alternatives like hCG.
Physicochemical and PK profile
- Half-Life
- ~10-40 minutes
- Storage
- Store the lyophilized vial refrigerated (2-8°C) or at -20°C, away from light. Once reconstituted, keep refrigerated at 2-8°C and use promptly.