VIP (Vasoactive Intestinal Peptide) Pharmacokinetics
VIP (Vasoactive Intestinal Peptide) half-life, absorption, routes of administration, and clearance.
Extremely Rapid Systemic Clearance
After IV administration, plasma VIP levels fall by first-order kinetics with an average disappearance half-time of about one minute — one of the shortest half-lives of any peptide in this catalog. This extremely rapid systemic clearance is why intranasal and subcutaneous routes, which create more sustained local/regional exposure, are preferred in research use over IV.
Physicochemical and PK profile
- Molecular Formula
- C147H238N44O42S
- Molecular Weight
- 3325.80 g/mol
- CAS Number
- 40077-57-4
- Half-Life
- ~1 minute (IV plasma disappearance)
- Storage
- Store the lyophilized vial refrigerated (2-8°C) or at -20°C, away from light. Once reconstituted, keep refrigerated at 2-8°C and use promptly.