Epithalon Mechanism of Action
How Epithalon works: receptor targets, signalling pathways, and molecular profile.
Pineal Peptide Analog
Epithalon (AEDG: Ala-Glu-Asp-Gly) is a synthetic tetrapeptide designed to mimic epithalamin, a naturally occurring pineal gland peptide extract. Research interest centers on the pineal gland's role in regulating melatonin production and, by extension, circadian rhythm and sleep-wake cycling.
Telomerase Activation Research
Epithalon is best known for preclinical research (Khavinson et al.) investigating telomerase activation — the enzyme that maintains telomere length at chromosome ends — in cell culture and animal models. This research forms the basis of its popularity in longevity circles, though direct human evidence for telomerase effects remains limited.