Epithalon Mechanism of Action
How Epithalon works: receptor targets, signalling pathways, and molecular profile.
Pineal Peptide Analog
Epithalon (AEDG: Ala-Glu-Asp-Gly) is a synthetic tetrapeptide designed to mimic epithalamin, a naturally occurring pineal gland peptide extract. Research interest centers on the pineal gland's role in regulating melatonin production and, by extension, circadian rhythm and sleep-wake cycling.
Telomerase Activation Research
Epithalon is best known for preclinical research (Khavinson et al.) investigating telomerase activation, the enzyme that maintains telomere length at chromosome ends, in cell culture and animal models. This research forms the basis of its popularity in longevity circles, though direct human evidence for telomerase effects remains limited.