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LL-37 Side Effects and Safety

Reported LL-37 side effects, contraindications, and safety signals.

RE
Compiled from published research · 1 min read · 3 references · Continuously updated
Safety

Undefined Human Safety Profile

No formal human safety or tolerability study exists for LL-37 administered as a standalone compound. Given its role in immune signaling, active autoimmune conditions are treated as a precautionary contraindication, along with pregnancy.

Contraindications

  • pregnancy
  • active autoimmune conditions

References

  1. Molecular Dynamics Simulations of Human Antimicrobial Peptide LL-37ncbi.nlm.nih.gov
  2. Immunomodulatory Functions of the Human Cathelicidin LL-37-Derived Peptidesncbi.nlm.nih.gov
  3. Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trialpubmed.ncbi.nlm.nih.gov · Grönberg A, Mahlapuu M, Ståhle M · 2014
All LL-37 sections

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