LL-37 Side Effects and Safety
Reported LL-37 side effects, contraindications, and safety signals.
Undefined Human Safety Profile
No formal human safety or tolerability study exists for LL-37 administered as a standalone compound. Given its role in immune signaling, active autoimmune conditions are treated as a precautionary contraindication, along with pregnancy.
Contraindications
- pregnancy
- active autoimmune conditions
References
- Molecular Dynamics Simulations of Human Antimicrobial Peptide LL-37
- Immunomodulatory Functions of the Human Cathelicidin LL-37-Derived Peptides
- Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial · Grönberg A, Mahlapuu M, Ståhle M · 2014