LL-37 Pharmacokinetics
LL-37 half-life, absorption, routes of administration, and clearance.
No Published Human PK Data
No formal human pharmacokinetic study — absorption, half-life, clearance — has been published for LL-37. Available data comes from in-vitro membrane-interaction studies and animal models rather than human plasma measurements.
Physicochemical and PK profile
- Molecular Formula
- C205H340N60O53
- CAS Number
- 597562-32-8
- Storage
- Store the lyophilized vial refrigerated (2-8°C) or at -20°C, away from light. Once reconstituted, keep refrigerated at 2-8°C and use promptly.
References
- Molecular Dynamics Simulations of Human Antimicrobial Peptide LL-37
- Immunomodulatory Functions of the Human Cathelicidin LL-37-Derived Peptides
- Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial · Grönberg A, Mahlapuu M, Ståhle M · 2014