Somatropin (HGH) Pharmacokinetics
Somatropin (HGH) half-life, absorption, routes of administration, and clearance.
Short Serum Half-Life, Longer Downstream Effect
Somatropin's serum half-life is short — roughly 20–30 minutes — but its biological effects last far longer because they're mediated through IGF-1, which has a much longer half-life and sustains the downstream metabolic and tissue effects well after the GH itself has cleared.
Physicochemical and PK profile
- Molecular Formula
- C990H1528N262O300S7
- Molecular Weight
- ~22,124 Da
- CAS Number
- 12629-01-5
- Half-Life
- ~20–30 minutes (serum)
- Storage
- Store the lyophilized vial refrigerated (2-8°C) or at -20°C, away from light. Once reconstituted, keep refrigerated at 2-8°C and use promptly.