GHRP-2 Side Effects and Safety
Reported GHRP-2 side effects, contraindications, and safety signals.
Safety & Contraindications
GHRP-2 is a research compound and is not FDA-approved for general use. It should be avoided by anyone with active malignancy and pregnancy. Most reported effects are mild and dose-dependent, so start at the low end of the dosing range and titrate up slowly rather than chasing a maximal dose. Injection-site redness, itching, or a temporary lump are the most common local reactions; rotate sites and use clean technique to keep them minimal.
What to Monitor
Track prolactin, IGF-1, and fasting glucose while you're running GHRP-2 so you can catch any drift early and adjust before it becomes a problem. Add these to your REGEN biomarker dashboard and re-check on your normal cadence.
Contraindications
- active malignancy
- pregnancy
References
- Growth hormone-releasing peptide-2 stimulates GH secretion · Bowers CY · 1998
- Arvat E, et al. Effects of GHRP-2 and hexarelin, two synthetic GH-releasing peptides, on GH, prolactin, ACTH and cortisol levels in man. Comparison with the effects of GHRH, TRH and hCRH. Peptides. 1997;18(6):885-891. · Arvat E, di Vito L, Maccagno B, Broglio F, Boghen MF, Deghenghi R, Camanni F, Ghigo E · 1997
- The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone. · Van den Berghe G, Baxter RC, Weekers F et al. · 2002
- Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide ... · 2004
- Mericq V, et al. Effects of eight months treatment with graded doses of a growth hormone (GH)-releasing peptide in GH-deficient children. Journal of Clinical Endocrinology & Metabolism. 1998;83(7):2355-2360. · Mericq V, Cassorla F, Salazar T, Avila A, Iñiguez G, Bowers CY, Merriam GR · 1998
- Synergy of L-arginine and GHRP-2 stimulation of growth hormone in men and women: modulation by exercise. · Wideman L, Weltman JY, Patrie JT et al. · 2000