Follistatin-344 Mechanism of Action
How Follistatin-344 works: receptor targets, signalling pathways, and molecular profile.
Blocking the Body's Brake on Muscle Growth
Follistatin-344 binds and neutralizes myostatin, a protein that normally restrains skeletal muscle growth by signaling through the activin receptor pathway. Animals and rare humans with naturally low myostatin activity show dramatically increased muscle mass — this real biology is the entire rationale behind follistatin as a muscle-growth research compound.
A Real Peptide, Unlike Steroidal Myostatin-Adjacent Compounds
Unlike steroidal compounds that claim myostatin-pathway effects as a side mechanism (e.g. YK-11), follistatin-344 acts directly and specifically on myostatin itself as its primary, dedicated mechanism — the most mechanistically 'clean' myostatin-inhibition approach among peptides sold in this space.
References
- A phase 1/2a follistatin gene therapy trial for Becker muscular dystrophy · Mendell JR, et al. · 2015