SS-31 (Elamipretide) Pharmacokinetics
SS-31 (Elamipretide) half-life, absorption, routes of administration, and clearance.
Short Half-Life, Rapid Mitochondrial Uptake
SS-31 has a plasma half-life of roughly 7-10 hours, but its relevant pharmacology is really about mitochondrial concentration rather than plasma persistence — it accumulates selectively in mitochondria-dense tissue (heart, skeletal muscle) far above plasma levels.
Physicochemical and PK profile
- Half-Life
- ~7-10 hours
- Storage
- Store the lyophilized vial refrigerated (2-8°C) or at -20°C, away from light. Once reconstituted, keep refrigerated at 2-8°C and use promptly.