Tirzepatide reconstitution calculator.
Pre-filled with the 10 mg vial and 2 mL of bacteriostatic water the REGEN catalog reports for Tirzepatide. Every field is editable.
The numbers for a 10 mg Tirzepatide vial
Reconstituting a 10 mg vial with 2 mL of bacteriostatic water gives a concentration of 5 mg/mL. On a U-100 insulin syringe, where one unit is 0.01 mL, that puts 50 mcg in every unit drawn.
A 2500 mcg dose at that concentration is 0.5 mL, which is 50 units on the syringe, and the vial holds about 4 of them.
Those are the values the calculator above opens with. The vial size and water volume are the amounts the REGEN catalog reports for Tirzepatide; change any field and the arithmetic follows.
What the research reports for Tirzepatide
Published protocols for Tirzepatide report 2.5–15 mg, 1x weekly (titrated). That is what the literature describes, not a recommendation. The calculator starts at the low end of it. The Tirzepatide reference page carries the evidence grade, the side-effect profile, and the primary sources behind that range.
Tirzepatide reconstitution chart for a 10 mg vial
The same 10 mg of Tirzepatide at four common water volumes. More water does not mean more compound, it spreads the same amount across a bigger volume, so the same dose is drawn to a higher number of units. That is usually the safer direction to be imprecise in: small errors on a longer draw matter proportionally less.
| Bacteriostatic water | Concentration | Per unit (U-100) | Units for 2500 mcg |
|---|---|---|---|
| 1 mL | 10 mg/mL | 100 mcg | 25 units |
| 2 mL (catalog) | 5 mg/mL | 50 mcg | 50 units |
| 3 mL | 3.33 mg/mL | 33.3 mcg | 75 units |
| 5 mL | 2 mg/mL | 20 mcg | 125 units |
"Units" here means syringe graduations, not international units. They are unrelated measures that share a name, and conflating them is its own category of mistake. The reconstitution calculator explains the arithmetic behind these columns in full.
More on Tirzepatide
The Tirzepatide reference page covers how it works, what the research grade means, side effects, and pharmacokinetics, alongside the rest of the weight loss compounds. For a different compound, the generic reconstitution calculator takes any vial and dose.