SS-31 (Elamipretide) reconstitution calculator.
Pre-filled with the 40 mg vial and 2 mL of bacteriostatic water the REGEN catalog reports for SS-31 (Elamipretide). Every field is editable.
The numbers for a 40 mg SS-31 (Elamipretide) vial
Reconstituting a 40 mg vial with 2 mL of bacteriostatic water gives a concentration of 20 mg/mL. On a U-100 insulin syringe, where one unit is 0.01 mL, that puts 200 mcg in every unit drawn.
A 40000 mcg dose at that concentration is 2 mL, which is 200 units on the syringe, and the vial holds about 1 of them.
Those are the values the calculator above opens with. The vial size and water volume are the amounts the REGEN catalog reports for SS-31 (Elamipretide); change any field and the arithmetic follows.
What the research reports for SS-31 (Elamipretide)
Published protocols for SS-31 (Elamipretide) report 40 mg, 1x daily. That is what the literature describes, not a recommendation. The calculator starts at the low end of it. The SS-31 (Elamipretide) reference page carries the evidence grade, the side-effect profile, and the primary sources behind that range.
SS-31 (Elamipretide) reconstitution chart for a 40 mg vial
The same 40 mg of SS-31 (Elamipretide) at four common water volumes. More water does not mean more compound, it spreads the same amount across a bigger volume, so the same dose is drawn to a higher number of units. That is usually the safer direction to be imprecise in: small errors on a longer draw matter proportionally less.
| Bacteriostatic water | Concentration | Per unit (U-100) | Units for 40000 mcg |
|---|---|---|---|
| 1 mL | 40 mg/mL | 400 mcg | 100 units |
| 2 mL (catalog) | 20 mg/mL | 200 mcg | 200 units |
| 3 mL | 13.33 mg/mL | 133.3 mcg | 300 units |
| 5 mL | 8 mg/mL | 80 mcg | 500 units |
"Units" here means syringe graduations, not international units. They are unrelated measures that share a name, and conflating them is its own category of mistake. The reconstitution calculator explains the arithmetic behind these columns in full.
More on SS-31 (Elamipretide)
The SS-31 (Elamipretide) reference page covers how it works, what the research grade means, side effects, and pharmacokinetics, alongside the rest of the longevity compounds. For a different compound, the generic reconstitution calculator takes any vial and dose.