PT-141 reconstitution calculator.
Pre-filled with the 10 mg vial and 5 mL of bacteriostatic water the REGEN catalog reports for PT-141. Every field is editable.
The numbers for a 10 mg PT-141 vial
Reconstituting a 10 mg vial with 5 mL of bacteriostatic water gives a concentration of 2 mg/mL. On a U-100 insulin syringe, where one unit is 0.01 mL, that puts 20 mcg in every unit drawn.
A 500 mcg dose at that concentration is 0.25 mL, which is 25 units on the syringe, and the vial holds about 20 of them.
Those are the values the calculator above opens with. The vial size and water volume are the amounts the REGEN catalog reports for PT-141; change any field and the arithmetic follows.
What the research reports for PT-141
Published protocols for PT-141 report 0.5–2 mg, as needed, before activity. That is what the literature describes, not a recommendation. The calculator starts at the low end of it. The PT-141 reference page carries the evidence grade, the side-effect profile, and the primary sources behind that range.
PT-141 reconstitution chart for a 10 mg vial
The same 10 mg of PT-141 at four common water volumes. More water does not mean more compound, it spreads the same amount across a bigger volume, so the same dose is drawn to a higher number of units. That is usually the safer direction to be imprecise in: small errors on a longer draw matter proportionally less.
| Bacteriostatic water | Concentration | Per unit (U-100) | Units for 500 mcg |
|---|---|---|---|
| 1 mL | 10 mg/mL | 100 mcg | 5 units |
| 2 mL | 5 mg/mL | 50 mcg | 10 units |
| 3 mL | 3.33 mg/mL | 33.3 mcg | 15 units |
| 5 mL (catalog) | 2 mg/mL | 20 mcg | 25 units |
"Units" here means syringe graduations, not international units. They are unrelated measures that share a name, and conflating them is its own category of mistake. The reconstitution calculator explains the arithmetic behind these columns in full.
More on PT-141
The PT-141 reference page covers how it works, what the research grade means, side effects, and pharmacokinetics, alongside the rest of the performance compounds. For a different compound, the generic reconstitution calculator takes any vial and dose.