BPC-157 Dosage and Protocols
BPC-157 dosage protocols reported in published research, plus reconstitution and storage.
Research Protocol Doses Reported in Published Literature
Research Disclaimer: Doses reported below are from published preclinical research protocols. BPC-157 is not approved for human use by the FDA or any regulatory agency. This information is provided for research reference only and does not constitute a dosing recommendation. All doses above are reported from published research protocols using laboratory subjects. Refer to the cited studies in the Research Studies section above for original source data.
BPC-157 Stability: Storage, Reconstitution, and Degradation Factors in Research
Lyophilized BPC-157 is highly stable when stored at -20°C, maintaining integrity for years. Once reconstituted in bacteriostatic water (BAC water), BPC-157 should be refrigerated at 2-8°C and used within 4-6 weeks for optimal activity. The peptide's unusual gastric stability—surviving extreme pH conditions—distinguishes it from most peptides, but in solution it remains susceptible to oxidation, hydrolysis, and bacterial contamination. Proper handling, including sterile technique and avoiding freeze-thaw cycles, is essential for research reproducibility.
Reported protocol doses
Reconstitution
A 5mg vial with 2mL of bacteriostatic water is the pairing reported most often. 5mg vial + 2mL bacteriostatic water = 2500mcg/mL. A 250mcg dose is 0.1mL (10 units on an insulin syringe).
Work out your own concentration with the reconstitution calculator.
Doses shown are those reported in published research, not a recommendation.
References
- Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract · Sikiric P, et al. · 2011
- Brain-gut axis and pentadecapeptide BPC 157 · Sikiric P, et al. · 2016
- Vasireddi N, et al. Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review. HSS Journal. 2025. · Vasireddi N, Hahamyan H, Salata MJ, Karns M, Calcei JG, Voos JE, Apostolakos JM · 2025
- Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain. · Lee E, Padgett B · 2021
- Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing · McGuire FP, Martinez R, Lenz A, Skinner L, Cushman DM · 2025
- Effect of BPC-157 on Symptoms in Patients with Interstitial Cystitis: A Pilot Study. · Lee E, Walker C, Ayadi B · 2024