TB-500 reconstitution calculator.
Pre-filled with the 5 mg vial and 2.5 mL of bacteriostatic water the REGEN catalog reports for TB-500. Every field is editable.
The numbers for a 5 mg TB-500 vial
Reconstituting a 5 mg vial with 2.5 mL of bacteriostatic water gives a concentration of 2 mg/mL. On a U-100 insulin syringe, where one unit is 0.01 mL, that puts 20 mcg in every unit drawn.
A 2000 mcg dose at that concentration is 1 mL, which is 100 units on the syringe, and the vial holds about 2 of them.
Those are the values the calculator above opens with. The vial size and water volume are the amounts the REGEN catalog reports for TB-500; change any field and the arithmetic follows.
What the research reports for TB-500
Published protocols for TB-500 report 2–5 mg, 2x weekly (loading), then 1x weekly. That is what the literature describes, not a recommendation. The calculator starts at the low end of it. The TB-500 reference page carries the evidence grade, the side-effect profile, and the primary sources behind that range.
TB-500 reconstitution chart for a 5 mg vial
The same 5 mg of TB-500 at four common water volumes. More water does not mean more compound, it spreads the same amount across a bigger volume, so the same dose is drawn to a higher number of units. That is usually the safer direction to be imprecise in: small errors on a longer draw matter proportionally less.
| Bacteriostatic water | Concentration | Per unit (U-100) | Units for 2000 mcg |
|---|---|---|---|
| 1 mL | 5 mg/mL | 50 mcg | 40 units |
| 2 mL | 2.5 mg/mL | 25 mcg | 80 units |
| 2.5 mL (catalog) | 2 mg/mL | 20 mcg | 100 units |
| 3 mL | 1.67 mg/mL | 16.7 mcg | 120 units |
| 5 mL | 1 mg/mL | 10 mcg | 200 units |
"Units" here means syringe graduations, not international units. They are unrelated measures that share a name, and conflating them is its own category of mistake. The reconstitution calculator explains the arithmetic behind these columns in full.
More on TB-500
The TB-500 reference page covers how it works, what the research grade means, side effects, and pharmacokinetics, alongside the rest of the recovery compounds. For a different compound, the generic reconstitution calculator takes any vial and dose.