LL-37 reconstitution calculator.
Pre-filled with the 5 mg vial and 2 mL of bacteriostatic water the REGEN catalog reports for LL-37. Every field is editable.
The numbers for a 5 mg LL-37 vial
Reconstituting a 5 mg vial with 2 mL of bacteriostatic water gives a concentration of 2.5 mg/mL. On a U-100 insulin syringe, where one unit is 0.01 mL, that puts 25 mcg in every unit drawn.
Those are the values the calculator above opens with. The vial size and water volume are the amounts the REGEN catalog reports for LL-37; change any field and the arithmetic follows.
What the research reports for LL-37
Published protocols for LL-37 report No standardized dose, no established human protocol. That is what the literature describes, not a recommendation. The dose field starts empty, because that figure does not convert to a single dose for this vial. The LL-37 reference page carries the evidence grade, the side-effect profile, and the primary sources behind that range.
LL-37 reconstitution chart for a 5 mg vial
The same 5 mg of LL-37 at four common water volumes. More water does not mean more compound, it spreads the same amount across a bigger volume, so the same dose is drawn to a higher number of units. That is usually the safer direction to be imprecise in: small errors on a longer draw matter proportionally less.
| Bacteriostatic water | Concentration | Per unit (U-100) |
|---|---|---|
| 1 mL | 5 mg/mL | 50 mcg |
| 2 mL (catalog) | 2.5 mg/mL | 25 mcg |
| 3 mL | 1.67 mg/mL | 16.7 mcg |
| 5 mL | 1 mg/mL | 10 mcg |
"Units" here means syringe graduations, not international units. They are unrelated measures that share a name, and conflating them is its own category of mistake. The reconstitution calculator explains the arithmetic behind these columns in full.
More on LL-37
The LL-37 reference page covers how it works, what the research grade means, side effects, and pharmacokinetics, alongside the rest of the recovery compounds. For a different compound, the generic reconstitution calculator takes any vial and dose.